《植物生理学报》 2013, 49(3): 225-233
通信作者:李德全;E-mail: dqli@sdau.edu.cn;Tel: 0538-8249137
摘 要:
促分裂原活化蛋白激酶(MAPK)级联途径在动物、植物和酵母中是高度保守的信号转导模型。MAPK级联途径通过“交谈”形成了复杂的信号传递网络, 将不同的细胞膜感受器与细胞应答联系起来, 响应生物和非生物胁迫, 并且在植物激素信号和生长发育进程中起重要的作用。MAPK级联途径由三种逐级磷酸化的蛋白激酶即MAPKKK、MAPKK和MAPK组成。AtMKK1是拟南芥MAPKK家族中的一员, 随着功能获得型突变体和功能缺失突变体的获得以及一些新型研究技术的应用, AtMKK1研究取得重要进展, 是目前研究较为详细的MAPKK。关键词:AtMKK1; MAPK级联途径; 信号转导; 胁迫响应
收稿:2012-11-20 修定:2013-02-06
资助:国家自然科学基金项目(31071337和31271633)。
Corresponding author: LI De-Quan; E-mail: dqli@sdau.edu.cn; Tel: 0538-8249137
Abstract:
Mitogen-activated protein kinase (MAPK) cascades are highly conserved signal transduction model in animals, plants and yeast. MAPK cascades form the complex signal transmission network through the “cross-talk” to connect diverse cell membrane receptors with cellular responses to response biotic and abiotic stresses, and play a central role in the hormone signal, growth and development process. MAPK cascades are consisted of MAPKKK, MAPKK and MAPK, through sequential phosphorylation. With the application of the loss-of- function mutant, the gain-of-function mutant and some new research techniques, the research of AtMKK1 has been made great progress and so far AtMKK1 has been comprehensively detailed as a member of MAPKK in Arabidopsis thaliana.Key words: AtMKK1; MAPK cascades; signal transduction; stress response
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